In a bowl, submerge the chicken thighs in the buttermilk. Make sure that the chicken thighs are fully submerged. Cover the bowl with plastic wrap. Then, refrigerate for at least 30 minutes (or overnight). This'll help the chicken become tender and flavorful.
Create the breadcrumbs mixture by combinining panko breadcrumbs, paprika, garlic powder, onion powder, dried oregano, salt, and black pepper in a shallow yet wide dish. Mix well.
Preheat your air fryer to 400ºF (204ºC) for 5 minutes.
Remove each chicken thigh from the buttermilk, allowing any excess liquid to drip off.
Coat each chicken thigh with the breadcrumb mixture, pressing gently to adhere the breadcrumbs to the chicken's surface. Ensure an even coating for a crunchy texture.
Lightly spray avocado oil on the air fryer basket to prevent sticking (optional).
Place the breaded chicken thighs in the preheated air fryer basket, leaving space between them for proper air circulation.
Air fry the chicken thighs at 400ºF (204ºC) for 16 - 22 minutes, flipping halfway through. The chicken should be golden brown and cooked at an internal temperature of 165ºF (74ºC).
Remove them from the air fryer once the chicken thighs are fully cooked and crispy. Let them rest for 5 minutes before serving to retain their juiciness.
Serve the air fried breaded chicken thighs with your favorite side dishes.